orphenadrine hydrochloride

Anti-muscarinic:Parkinsonism Drug induced extrapyramidal symptoms

150–400 mg daily in divided doses

Molecular weight :305.8

%Protein binding :95

%Excreted unchanged in urine : 8

Volume of distribution (L/kg) :No data

half-life – normal/ESRD (hrs) :14/–

20 to 50 : Dose as in normal renal function

10 to 20 : Dose as in normal renal function

<10 : Dose as in normal renal function

CAPD :Unlikely dialysability. Dose as in normal renal function

HD :Unlikely dialysability. Dose as in normal renal function

HDF/high flux :Unlikely dialysability. Dose as in normal renal function

CAV/VVHD :Unlikely dialysability. Dose as in normal renal function

Potentially hazardous interactions with other drugs

None known

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Oral

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